Design (sign #2) should work to highlight content (sign #1). The most important content should be the first thing visible on the site. This is done correctly by utilizing the design. By using color, size, photos, and other interesting visual elements, we can direct the eye to what we want the user to see first, second, third, etc. This is mostly transparent to the user, but it really works.
By understanding the content and knowing the heirarchy of information, the design is used as part of the communication tool.
The Jeannie Bottle Art Car Proposal website demonstrates a successful design because it: